Difficulty breathing and headache often indicate inflammation of the maxillary sinus of the nose. In a scientific way, such a pathology is called sinusitis. Of the inflammatory processes of the paranasal sinuses, the disease is the most common.
Despite the various methods of treatment, it is not always possible to get rid of the symptoms of chronic antritis for a long time. Sometimes symptoms periodically occur, regardless of the therapy. In such cases, prescribe potent drugs.
Dioxidine is considered one of them.
This drug is an antimicrobial. It is prescribed in cases where inflammation is caused by bacteria that are resistant to antibiotics.
The drug is used only when running forms of sinusitis, as it has a number of contraindications. Therefore, its use without the appointment of an otolaryngologist is not recommended. How to use Dioxidine for sinus, decides the attending physician.
There are several ways to use the drug.
The mechanism of action of the drug
Dioxidine is a potent medicinal substance that has been used for the treatment of purulent inflammatory processes for several decades. It affects a large number of pathogenic bacteria, leading to their death.
Therefore, the drug is called a broad spectrum antiseptic.
The bacteria that are affected by the drug include:
- Staphylococcus. This microorganism often leads to the development of a purulent process in the maxillary sinuses.
- Streptococcus. Chronic infection is dangerous with complications of the urinary and cardiovascular systems.
- Meningococci. Often they cause a disease like nasopharyngitis. With late treatment, it is complicated by purulent sinusitis and meningitis.
- Pseudomonas aeruginosa. Pathologies caused by this pathogen are referred to as intrahospital infections. They are difficult to treat with antibiotics.
The drug is also effective in inflammation caused by Gram (-) bacteria, actinomycetes and other microorganisms. The drug provides antiseptic, anti-inflammatory and regenerative effects.
The mechanism of action of Dioxidin is the destruction of the genome of pathogens. Due to this stops the reproduction of bacteria in the inflammation.
Indications for appointment
The drug is recommended to be used only in cases when other drugs do not bring effect. Indications for the use of the drug are any purulent inflammatory processes.
Local use of dioxidine is most common. Medicinal solution is recommended to enter directly into the pathological focus.
In rare cases, intravenous administration of Dioxidine is provided (when the infection spreads throughout the body).
In otolaryngology, the following indications for prescribing the drug are distinguished:
- The accumulation of purulent exudate in the maxillary sinuses.
- The lack of effect of antibiotic treatment.
- Surgical intervention in the paranasal sinuses.
Most often, Dioxidine is indicated for purulent sinus, but it can also occur with complicated rhinitis and other sinusitis (frontal, ethmoiditis), pharyngeal inflammation. The medicinal solution is usually used to wash the sinuses after the puncture. This allows the sinus to be emptied of pus or contributes to the destruction of pathogenic microorganisms.
Dioxidine is injected into the cavity of the maxillary sinuses, both before and after surgery.
Side effects and contraindications
It should be remembered that the medication is prescribed only in the case when it is impossible to choose an alternative drug. The main contraindications to its use are children under the age of 12 years, pregnancy and lactation.
Some sources indicate that the drug can not be prescribed to minors. However, in severe cases, this rule is neglected for health reasons (the threat of sepsis and meningitis).
Prescription medication during pregnancy can lead to the development of genetic abnormalities in the fetus.
Dioxidine is prohibited in case of intolerance to the active substance. Also, it can not be used in the pathologies of the adrenal glands.
It adversely affects the functioning of these endocrine glands. The drug is excreted by the kidneys, therefore, in severe forms of ESRD, it is categorically contraindicated.
Among the side effects are: sleep disturbance, dizziness, gastrointestinal disorders (nausea, vomiting, diarrhea), convulsive syndrome, itching and skin rash. With the development of any unwanted symptom, the doctor will consider withdrawing the drug.
There are several dosage forms in which Dioxidin is produced. Among them – nasal drops, ointment and solution. The choice of method of use of the drug depends on each specific case.
In most cases, washing of the maxillary sinuses with a 0.5% Dioxidine solution is prescribed after a puncture or during surgery. If the indication for the purpose of the medication is the ineffectiveness of other medicines, the drug may be prescribed in ointment form or as part of complex nasal drops.
Intravenous administration of Dioxidine is an emergency measure for the penetration of bacterial pathogens into the blood.
Inhalation with the drug
In some cases, the doctor prescribes inhalation with dioxidine. For its preparation using 0.5 or 1% solution. Inhalation can be done no more than 2 times a day.
They are prescribed for severe sinusitis. The preparation is diluted as follows: for 1 ml of 0.5% Dioxidine solution there is 2 ml of NaCl 0.9%.
The temperature of the obtained drug should be equal to 20 degrees Celsius. 1 ml of 1% Dioxidine solution is diluted in 2 ml of HaCl.
Before the procedure, clean the nasal passages. For inhalation requires about 4 ml of the drug. The duration of the procedure should not exceed 3 minutes.
Diluted Dioxidine can be stored in the refrigerator for 12 hours.
Instill nasal passages
To prepare the nasal drops, use the dioxidine solution in vials. You can also use the drug from the ampoule.
In its pure form, medication is prescribed rarely. The most commonly used combination (complex) drops, which are prepared in specialized pharmacies.
They consist of: Dioxidine, steroid anti-inflammatory drugs (Hydrocortisone, Dexamethasone) or adrenaline. Sometimes other vasoconstrictor components are added, for example, Naphthyzinum. It is shown to dig in each nostril no more than 1 / 2-1 / 3 pipettes from 3 to 5 times a day.
The course of treatment is 7 days.
Ointment form of the drug
In most cases, in chronic sinus the doctors prescribe treatment with the ointment form of Dioxidin. The drug helps not only to destroy the bacteria, but also to eliminate the swelling of the mucous membranes of the nose and paranasal sinuses.
The result is the purification of the sinuses from pus, reduction of headaches and the release of the respiratory tract. Before laying the drug should clear the nasal passages using furatsilina solution. The ointment is squeezed out in a small amount and applied to previously prepared cotton wool coats.
The nose should be massaged for a few minutes for normal distribution of the drug through the mucosa. The use of ointment with Dioxidin should not exceed 3 weeks.
The drug is a toxic drug, so the reviews about it are contradictory. It is worth remembering that the likelihood of side effects is high. Patient reviews: